Pesquisa sobre: RECEPTOR TYROSINE KINASE-LIKE ORPHAN RECEPTORS 
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Descritor Inglês:   Receptor Tyrosine Kinase-like Orphan Receptors 
Descritor Espanhol:   Receptores Huérfanos Similares al Receptor Tirosina Quinasa 
Descritor Português:   Receptores Órfãos Semelhantes a Receptor Tirosina Quinase 
Categoria:   D08.811.913.696.620.682.725.400.093
D12.776.543.750.060.233
Definição Inglês:   A family of cell surface receptors that were originally identified by their structural homology to neurotropic TYROSINE KINASES and referred to as orphan receptors because the associated ligand and signaling pathways were unknown. Evidence for the functionality of these proteins has been established by experiments showing that disruption of the orphan receptor genes results in developmental defects. 
Nota de Indexação Inglês:   do not confuse with ORPHAN NUCLEAR RECEPTORS
Nota Histórica Inglês:   2010 
Qualificadores Permitidos Inglês:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DU diagnostic use
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Número do Registro:   53614 
Identificador Único:   D057050 

Ocorrência na BVS:
 

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